Using generative chemistry to design oral medicines that enhance and extend life.
Foundation models for protein dynamics and generative chemistry.
Trained on proprietary datasets, including physics simulations, our foundation models simultaneously generate small-molecule ligands and the protein conformations they induce. By capturing how proteins move and adapt, we uncover new binding pockets and chemical scaffolds that traditional methods miss.
Unlocking challenging targets
We apply our platform to find new chemical starting points and optimize them against difficult targets with high therapeutic potential. We started with GPCRs and we are expanding into channels, enzymes, and protein interfaces. We design not just initial hits but compounds with the full spectrum of potency, selectivity, and druglike properties needed to efficiently advance to the clinic.
Partnering
Oral medicines that extend lifespan & healthspan
Our goal is to rapidly translate breakthroughs in molecular design into oral medicines that improve health and extend lives. We focus on major unmet medical needs where accessible, convenient treatments can benefit millions of patients.